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pentobarbital will minimize the level or result of ritonavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.pentobarbital decreases levels of panobinostat by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Powerful CYP3A4 inducers can minimize panobinostat concentrations by ~70% and result in pro